Limassol Drugs Company Ltd

Limassol Drugs Pharmaceutical Products

Debridement

 

Debridement is a basic necessity to induce the functional process of tissue repair, especially in chronic wounds.

 

In this pilot study the authors used a new debrider technology with specific monofilament fibres in a unique texture to evaluate its efficacy, safety and tolerability.

In 11 patients, exhibiting all types of woundassociated debris (biofilms, slough, necrotic crusts and hyperkeratotic plaques), the debrider, wetted with physiological solution, was wiped without specific force over the wound for about 2–4 minutes.

This led to removal of almost all debris leaving healthy granulation tissue intact, including small epithelialized islands of vital tissue. The procedure was without pain and adverse events. Scanning electron microscopic analyses identified the majority of the removed debris tightly packed within the monofilament texture.

A surgeon who blindly assessed pictures taken before and after the debridement categorized all except one wound without the need for surgical debridement and ranked all the debridement results with the new debrider as ‘very good’ (best category).

 

This formulates the basic concept that the new debrider-based technology is easy, fast, highly efficient, well tolerated and cost effective.

 

Exudating, seropurulent wound with highly viscous yellow slough indicative of local infection and a bacterial biofilm (patient 1); (b) The debrider
removes the vast majority of these coatings and leads to vital tissue.

 

Dry wound specifically suffering from serocrusts between the new vital granulation and epithelialization tissue (patient 2); (b) The debrider
selectively removes the crusts without affecting the new healthy tissue.

 

 

Debridement Key points

 

Debridement is a basic necessity to induce or allow the functional process of tissue repair, especially in chronic wounds

 

• In this prospective, blindly assessed pilot study the authors used a new debrider technology with specific monofilament fibres in a unique texture to evaluate its efficacy, safety and tolerability

 

• The new debrider led to the removal of almost all debris, but importantly left healthy granulation tissue including small epithelialized islands of vital tissues intact

 

 Patients did not feel any adverse symptoms during the debridement process, in particular no pain, and the health professional’s global assessment revealed that the use of the debrider was easy, fast and efficient.

 

A surgeon blindly assessed all pictures taken before treatment, categorized all except one wound without the need for surgical debridement and ranked all the debridement results with the new  ebrider as ‘very good’ and the one wound formerly classified as needing surgical debridement as ‘equal to surgical debridement’

 

• The new debrider with its specific monofilament fibres offers a simple, safe and easy-to-access debridement technique and enables a broad use; it is anticipated that the use of the new debrider could save substantial costs